Country of Origin: United Kingdom
CAS No.: 53-19-0
Appearance: White Powder
Molecular formula: C14H10Cl4
Average Lead Time: Within 12 hours after receiving your payment
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Pharmaceutical Raw Materials Mitotan CAS 53-19-0 Used to
Air & Water Reactions:Insoluble in water.
Chemical Properties:White Crystalline Solid
Usage:insecticide, antineoplastic. treatment of osteoporosis and
Paget's bone disease. Used as an adrenolytic agent
Mitotane Simple aromatic halogenated organic compounds are very
unreactive; halogenated aliphatic compounds are moderately or very
reactive. For both subgroups, reactivity generally decreases with
increased degree of substitution of halogen for hydrogen atoms.
Materials in this group are incompatible with strong oxidizing and
reducing agents. Also, they are incompatible with many amines, nitrides,
azo/diazo compounds, alkali metals, and epoxides.
Mitotane structure and pharmacological action insecticide DDT (DDT) and
DDD similar, it selectively adrenal zona fasciculata and reticularis
cells atrophy, necrosis, but does not affect the zona, aldosterone
secretion and therefore will not be affected. Blood and urine cortisol
and its metabolites rapidly reduced after treatment, the body
adrenocorticotropic hormone and metabolism products decreased rapidly,
for the treatment of inoperable, functional and non-functional adrenal
cortical carcinoma, adrenal tumor, adrenal gland cruzi induced
hyperplasia syndrome, adrenal hyperplasia, cortical cancer adjuvant
therapy and tumor-induced Cushing's syndrome.